3D-QSAR, Molecular Docking, Molecular Dynamics Simulations and Structural Studies of Some Selected Inhibitors of the Glycoprotein (GPC) of Lassa Virus
3D-QSAR, Molecular Docking, Molecular Dynamics Simulations and Structural Studies of Some Selected Inhibitors of the Glycoprotein (GPC) of Lassa Virus

Emmanuel Israel Edache; Hadiza Adamu Dawi; Fabian Audu Ugbe

Volume 3, Issue 3 , July 2023, , Pages 224-244

https://doi.org/10.48309/jaoc.2023.410946.1103

Abstract
  3D-QSAR, comparative molecular field analysis- smart region description (SRD) and fractional factorial design (FFD) (CoMFA-FFD), and comparative molecular field analysis-uninformative ...  Read More
In Silico Molecular Docking Against-KIT Tyrosine Kinase and ADME Studies of 4-Thiazolidinone Derivatives
In Silico Molecular Docking Against-KIT Tyrosine Kinase and ADME Studies of 4-Thiazolidinone Derivatives

Deepak Shankar Kadam; Sudhakar G Patil; Denni Mammen; Shreyash Deepak Kadam; Vijaykumar Shivdas More

Volume 3, Issue 1 , January 2023, , Pages 13-27

https://doi.org/10.22034/jaoc.2023.355363.1058

Abstract
  Thiazolidin-4-one derivatives have been hailed as “wonder nucleus” due to their profound biological activities. A number of derivatives with variable functional groups attached ...  Read More
Antituberculosis Activity, Synthesis of 3-((1H-Benzo[d]imidazol-2-ylthio)methyl)-2-chloroquinoline Derivatives Using Copper Nanoparticles Grafted on Carbon Microspheres
Antituberculosis Activity, Synthesis of 3-((1H-Benzo[d]imidazol-2-ylthio)methyl)-2-chloroquinoline Derivatives Using Copper Nanoparticles Grafted on Carbon Microspheres

Maroti Madhavrao Dhange; Shivaji Balwant Patwari; Nitishkumar Suryakant. Kaminwar; Balaji Rajendra Madje; Dhanji P. Rajani; Rajkumar Uddhavrao Pokalwar

Volume 3, Issue 1 , January 2023, , Pages 39-51

https://doi.org/10.22034/jaoc.2023.359825.1061

Abstract
  The copper nanoparticles grafted on carbon microsphere (Cu-NP/C) catalyst was used to create a convenient and efficient synthesis of 3-(1H-benzo(d)imidazole-2-yithio) methyl-2-chloroquinoline ...  Read More
Synthetic Impatienol analogues as potential cyclooxygenase-2 inhibitors: a preliminary study
Synthetic Impatienol analogues as potential cyclooxygenase-2 inhibitors: a preliminary study

Garima Sharma; S. B. Sharma

Volume 1, Issue 2 , April 2021, , Pages 66-75

https://doi.org/10.22034/jaoc.2021.276815.1006

Abstract
  Cyclooxygenase (COX) is a key enzyme in the biosynthetic pathway leading to the formation ofprostanoids, including prostaglandins, prostacyclin and thromboxane, which are mediatorsof ...  Read More