Kinetic and Thermodynamic Aspects of Phosphate Diester Hydrolysis in Alkaline Solutions: The Role of Non-Leaving Groups
Kinetic and Thermodynamic Aspects of Phosphate Diester Hydrolysis in Alkaline Solutions: The Role of Non-Leaving Groups

Khaled Muftah Elsherif; Mohamed Suliman Sasi; Abdulfattah Mohamed Alkherraz; Mariam Salem Elayeb

Volume 4, Issue 1 , January 2024, , Pages 1-13

https://doi.org/10.48309/jaoc.2024.423269.1134

Abstract
  Alkaline hydrolysis of phosphate diester compounds with a common leaving group (LG) and varying non-leaving groups (NLG) was investigated. The nitrophenyl group was employed as a leaving ...  Read More
Molecular Docking, Molecular Dynamics Simulation, and MM/GBSA Studies of (N-(4-Carbamoylphenyl)-8-cyclopropyl-7-(naphthalen-1-ylmethyl)-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxamide for Its Potential Use Against SARS-CoV-2
Molecular Docking, Molecular Dynamics Simulation, and MM/GBSA Studies of (N-(4-Carbamoylphenyl)-8-cyclopropyl-7-(naphthalen-1-ylmethyl)-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxamide for Its Potential Use Against SARS-CoV-2

Emmanuel Israel Edache; Adumu Uzairu; Paul Andrew Mamza; Gideon Adamu Shallangwa; Muhammad Tukur Ibrahim

Volume 3, Issue 4 , November 2023, , Pages 321-345

https://doi.org/10.48309/jaoc.2023.423447.1135

Abstract
  Coronavirus disease 2019 (COVID-19) is a pandemic disease caused by the SARS-coronavirus-2, which has a high rate of infection. Regardless of the advancements made in the creation of ...  Read More
Approaches for Special Characteristics of Chalcogen Bonding: A Mini Review
Approaches for Special Characteristics of Chalcogen Bonding: A Mini Review

Humphrey S Samuel; Emmanuel ETIM; Ugo Nweke-Maraizu

Volume 3, Issue 3 , July 2023, , Pages 199-212

https://doi.org/10.22034/jaoc.2023.405432.1089

Abstract
  Chalcogen bonding, an intriguing and relatively new noncovalent contact, has drawn a lot of interest in the field of chemical bonding because of its special characteristics and possible ...  Read More
Kinetic and Thermodynamics Analysis: Effect of Eudragit Polymer as Drug Release Controller in Electrospun Nanofibers
Kinetic and Thermodynamics Analysis: Effect of Eudragit Polymer as Drug Release Controller in Electrospun Nanofibers

Fatemeh Tavakoli; Hadi Shafiei; Reza Ghasemikhah

Volume 2, Issue 4 , October 2022, , Pages 209-217

https://doi.org/10.22034/jaoc.2022.155078

Abstract
  The purpose of the present study was investigating kinetic and thermodynamic analysis using eudragit (EUD) polymer as controller to drug release mebendazole. nanofibers containing various ...  Read More