Sami Publishing CompanyJournal of Applied Organometallic Chemistry2783-36231120210201Iodine‐DMSO Catalyzed aromatization of Polysubstituted Cyclohexanone derivatives; An efficient methods for the synthesis of polyfunctionized Biaryls derivatives1812853810.22034/jaoc.2021.128538ENSunil V.GaikwadDepartment of Chemistry, Centre for Advanced Research, Savitribai Phule Pune University, Pune 411007, India0000-0003-0754-1945Milind V.GaikwadDepartment Of Chemistry, Dr. D. Y. Patil A.C.S. College, Pimpri, Savitribai Phule Pune University Pune- 411018, India0000-0001-5917-6455Pradeep D.Lokhande1Department of Chemistry,a Centre for Advanced Research, Savitribai Phule Pune University, Pune 411007, India0000-0001-5948-620XJournal Article20210301Abstract<br />We have developed a simple method for the regioselective aromatization of Polysubstituted Cyclohexanone derivatives in the presence of iodine (25 mol %), Pd/C (10Mol%) in dimethyl sulfoxide at 90 °C. , afforded functionalized biphenyls with at least one phenolic hydroxyl in moderate to very good yields. The present protocol contains a cheap catalyst, easy work up, normal reaction conditions, and high selectivity.https://jaoc.samipubco.com/article_128538_1a89491a2d097298d90a184e8385216d.pdfSami Publishing CompanyJournal of Applied Organometallic Chemistry2783-36231120210201Simple and efficient synthesis of 2-styryl-4H-chromone-4-one derivatives by modification of the Baker-Venkataraman method91612859610.22034/jaoc.2021.275519.1001ENBaliram S.HoteDepartment of Chemistry, Maharashtra Udayagiri Mahavidyalaya Udgir, 413 517, Maharashtra, Indiaorcid.org/0000-0002-8990-9346Dyanoba B. MuleyDepartment of Chemistry, Shivaji Mahavidyalaya Udgir, 413 517, Maharashtra, India0000-0001-6653-2307Gajanan G. MandawadDepartment of Chemistry, Maharashtra Udayagiri Mahavidyalaya Udgir, 413 517, Maharashtra, India0000-0002-5317-2637Journal Article20210301The efficient and facile protocol was developed for the synthesis of 2-styryl-4H-chromen-4-one 3a-i derivatives. The condensation of substituted 2-hydroxyacetophenone with cinnamic acid to obtained (E)-2-acetylphenylcinnamate 2a-i derivatives, which on treatment with base leads to target 3a-i derivatives. A wide range of functional groups were tolerated in the developed protocol. The target molecules were obtained in good to excellent yield applying the current method. All target compounds are characterized by IR, 1H NMR, and 13C NMR spectral data.https://jaoc.samipubco.com/article_128596_134d14fb09208c43065b3f3e927ddf99.pdfSami Publishing CompanyJournal of Applied Organometallic Chemistry2783-36231120210201Ninhydrin as a novel and efficient catalyst for the synthesis of 2-amino-4H-Pyran derivatives in aqueous media using172112867210.22034/jaoc.2021.277050.1007ENBita BaghernejadDepartment of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, Iran0000-0002-1733-0829Mahsa FiuzatDepartment of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, Iran0000-0003-3492-7341Journal Article20210310< p>Benzopyranes and their derivatives are of interest due to their wide range of biological and medicinal properties. In this study, 2-amino-4H-pyran derivatives were obtained through a one-step multi-component reaction of aromatic aldehyde, malononitrile and dimedone in the presence of ninhydrin as a catalyst in water with high efficiency and short time.https://jaoc.samipubco.com/article_128672_4d40a9d46f9218f96af565ec8bd310ca.pdfSami Publishing CompanyJournal of Applied Organometallic Chemistry2783-36231120210201DTP/SiO2:An Efficient And Reusable Heterogeneous Catalyst For synthesis of dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives222812882310.22034/jaoc.2021.276239.1004ENRahul D.KambleDepartment of Chemistry, Amruteshwar ACS, College, Vinzar, Pune (MS) India-4122130000-0003-4994-9818Milind V.GaikwadDepartment of Chemistry, D.Y. Patil ACS, College, affiliated; Savitribai Phule Pune University, Pimpri, Pune (MS) India-411018https://orcid.org/00Manojkumar R.TapareDepartment of Chemistry, Amruteshwar ACS, College, Vinzar, Pune (MS) India-4122130000-0003-1968-9189Shrikant VHeseDepartment of Chemistry, DD Bhoyar College, Mouda, Nagpur (MS) India-4411040000-0002-5274-1148Shuddhodan NKadamDepartment of Chemistry, Vidnyan Mahavidhyalaya, Sangola, Solapur (MS) India 4133070000-0003-3791-3498Ajay NAmbhoreDepartment of Chemistry, PDVP College, Tasgaon, Sangali (MS) India 4163120000-0002-0993-2440Bhaskar S.DawaneSchool of Chemical Sciences, SRTM University, Nanded (MS) India 4316060000-0003-2359-90182Journal Article20210304An efficient and convenient method has been developed for the synthesis of 2-amino-5-oxo-4-phenyl-4, 5-dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives from one-pot multicomponent reaction between 4-hydroxy-2H-chromen-2-one, aromatic aldehydes and malononitrile catalyzed by DTP/SiO2 as an efficient and reusable heterogeneous catalyst. The current method provides adavtages over reported method viz simple operational procedure, easy isolation and recyclability of the catalyst, environmental benign, reduced reaction time and superior yield.https://jaoc.samipubco.com/article_128823_b19fb659fbd1df9ee404e030a76ca8b7.pdfSami Publishing CompanyJournal of Applied Organometallic Chemistry2783-36231120210201Computational Chemistry Approach for the Investigation of Structural, Electronic, Chemical and Quantum Chemical Facets of Twelve Biginelli Adducts294012905110.22034/jaoc.2021.278598.1009ENVishnu AAdolePG Department of Chemistry, Mahatma Gandhi Vidyamandir’s Arts, Science and Commerce College, Manmad, Taluka-Nandgaon, District- Nashik, India-423104.0000-0001-7691-7884Journal Article20210307The rising concerns about the Biginelli reaction are mainly attributable to the therapeutic and pharmacological features of Biginelli adducts, especially dihydropyrimidinones (DHPMs). The DFT framework could be used to explore molecular properties such as molecular structures, molecular energies, ionisation potentials, dipole moments, and electronic parameters. It also contributes to the correlative analysis of theoretical and experimental findings through providing valuable perspectives. Using density functional theory (DFT) at the 6-311++G(d,p) basis set, twelve Biginelli adducts were focused to ascertain various structural and chemical parameters. The important structural parameters such as optimized molecular structures, frontier molecular orbital (FMO) analysis, and molecular electrostatic potential analysis were addressed in the present report. In addition, different quantum chemical parameters have been calculated to gain a deeper comprehension of the molecules' synthetic reactivity. The FMO and quantum chemical exploration revealed that BA7 molecule has a lower HOMO-LUMO energy gap, indicating that charge transfer interactions are inevitable within the molecule. The BA7 molecule was also found to have a higher global softness value than the other derivatives. The absolute hardness of the BA6 molecule, on the other hand, is higher. With a value of 2.3228 eV, the BA3 molecule was revealed to have the highest charge transfer.https://jaoc.samipubco.com/article_129051_c817f8097789302f8e63e1701c9f2f7b.pdfSami Publishing CompanyJournal of Applied Organometallic Chemistry2783-36231120210201Synthesis, Spectral and Biological Studies of DHA Schiff Bases414712925810.22034/jaoc.2021.275758.1003ENShubham Bhagwatrao BiradarDepartment of Chemistry, Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur (M. S.), India0000-0003-4270-4738Dnyaneshwar Vithal NarteDepartment of Chemistry, Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur (M. S.), India0000-0001-5458-1945Rushikesh Pradip KaleDepartment of Chemistry, Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur (M. S.), India0000-0002-7133-4820Kalimoddin InayatsabMominDepartment of Chemistry, Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur (M. S.), India.0000-0001-6297-6509Maroti SayabuSudewadDepartment of Chemistry, Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur (M. S.), India.Kundan ChandramaniTayadeDepartment of Chemistry, Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur (M. S.), India.https://orcid.org/00Dhananjay GangadharPalkeDepartment of Chemistry, Rajarshi Shahu Mahavidyalaya, (Autonomous) Latur (M. S.), India0000-0003-4994-9818Journal Article20210302ABSTRACT<br />A new series of Schiff bases derived from DHA (Dehydroacetic acid) and aromatic primary amines were synthesized and characterized by elemental and spectral (Electronic, IR and 1HNMR) analysis. The signals of 1HNMR spectrum and characteristic peaks in IR spectra are used for the molecular structure elucidation of synthesized Schiff bases. The antimicrobial activities of synthesized compounds have been screened in vitro against Escherichia coli, Staphylococcus aureus, Bacillus subtilis bacterial species, Candida albicans and Aspergillus niger fungal organism and found to exhibit strong antifungal activity than antibacterial activity. Among the studied DHA Schiff base of 2-amino-4,6-dimethylpyrimidine depicted discerning antifungal and antibacterial activities.https://jaoc.samipubco.com/article_129258_13d40058c776273d92a3adeddc5f343d.pdf