Document Type : Short Communication
- Sadashiv Sahebrao Nagre
- Namdeo Tukaram Dhokale
- Navnath Ramkrishna Dalvi
- Satish Bhaskarrao Kale
- Shankaraiah Guruvaiah Konda
Department of Chemistry, K. J. Somaiya College, Kopargaon-423601, (M.S.), India
In this present investigation, an efficient protocol for the synthesis of bundle of novel substituted benzo[h]quinazoline-2(3H)-thione derivatives was reported. The acetic acid catalyzed benzo[h]quinazoline-2(3H)-thione derivatives were prepared from 2-(substituted arylidene)-1-tetralones, thiourea and green solvent polyethylene glycol-400 with efficient and milder reaction condition. All the novel scaffolds were confirmed by the spectroscopic methods (IR, 1H NMR, Mass and Elemental analysis). The superiority of present method was operational simplicity, easy purification; high yields, easy available catalyst, environmental friendly solvent.