Iodine‐DMSO Catalyzed aromatization of Polysubstituted Cyclohexanone derivatives; An efficient methods for the synthesis of polyfunctionized Biaryls derivatives
1. Iodine‐DMSO Catalyzed aromatization of Polysubstituted Cyclohexanone derivatives; An efficient methods for the synthesis of polyfunctionized Biaryls derivatives

Sunil V. Gaikwad; Milind V. Gaikwad; Pradeep D. Lokhande

Volume 1, Issue 1 , February 2021, , Pages 1-8

http://dx.doi.org/10.22034/jaoc.2021.128538

Abstract
  AbstractWe have developed a simple method for the regioselective aromatization of Polysubstituted Cyclohexanone derivatives in the presence of iodine (25 mol %), Pd/C (10Mol%) in dimethyl ...  Read More
Acetic Acid Catalyzed Synthesis of Benzo[h]quinazoline-2(3H)-thione Derivatives Using Polyethylene glycol--400 as Green Reaction Medium
2. Acetic Acid Catalyzed Synthesis of Benzo[h]quinazoline-2(3H)-thione Derivatives Using Polyethylene glycol--400 as Green Reaction Medium

Shankaraiah Guruvaiah Konda; Sadashiv Sahebrao Nagre; Namdeo Tukaram Dhokale; Navnath Ramkrishna Dalvi; Satish Bhaskarrao Kale

Volume 2, Issue 1 , January 2022, , Pages 1-6

http://dx.doi.org/10.22034/jaoc.2022.319818.1042

Abstract
  In this present investigation, an efficient protocol for the synthesis of bundle of novel substituted benzo[h]quinazoline-2(3H)-thione derivatives was reported. The acetic acid catalyzed ...  Read More
Synthesis of (±)-Baclofen using Wittig Olefination–Claisen Rearrangement
3. Synthesis of (±)-Baclofen using Wittig Olefination–Claisen Rearrangement

Deekshaputra Ramrao Birhade; Rohit Gulab Shinde; Mahendra Nanduram Lokhande; Milind Dhondiba Nikalje

Volume 1, Issue 3 , July 2021, , Pages 109-115

http://dx.doi.org/10.22034/jaoc.2021.284219.1018

Abstract
  Baclofen, a lipophilic derivative of GABA (gamma-Aminobutyric acid), which acts as an inhibitory neurotransmitter in CNS (central nervous system) was synthesized by Witting olefination-Claisen ...  Read More
A novel approach for total synthesis of Stemona alkaloid: Tuberostemonamide
4. A novel approach for total synthesis of Stemona alkaloid: Tuberostemonamide

Mir Monir Hossain; Tasmuna Tamrin Tanmy

Volume 1, Issue 4 , October 2021, , Pages 159-164

http://dx.doi.org/10.22034/jaoc.2021.304913.1037

Abstract
  Stemona alkaloids, are structurally complex and polycyclic alkaloids, obtained from a novel class of natural plants which are extracted, separated, and purified from Stemonaceae family. ...  Read More
Ammonium chloride catalyzed Green synthesis, characterization of substituted 1-H-indazole derivatives
5. Ammonium chloride catalyzed Green synthesis, characterization of substituted 1-H-indazole derivatives

Milind Gaikwad; Ravina Jadhav; Monika Dalvi; Anil Nagane

Volume 2, Issue 1 , January 2022, , Pages 7-14

http://dx.doi.org/10.22034/jaoc.2022.324460.1045

Abstract
  We have demonstrated novel and eco-friendly acceptable green methods for the synthesis of numerous 1-H-indazole by grinding protocol using NH4Cl milder acids in an EtOH solvent. The ...  Read More
Simple and efficient synthesis of 2-styryl-4H-chromone-4-one derivatives by modification of the Baker-Venkataraman method
6. Simple and efficient synthesis of 2-styryl-4H-chromone-4-one derivatives by modification of the Baker-Venkataraman method

Baliram S. Hote; Dyanoba B. Muley; Gajanan G. Mandawad

Volume 1, Issue 1 , February 2021, , Pages 9-16

http://dx.doi.org/10.22034/jaoc.2021.275519.1001

Abstract
  The efficient and facile protocol was developed for the synthesis of 2-styryl-4H-chromen-4-one 3a-i derivatives. The condensation of substituted 2-hydroxyacetophenone with cinnamic ...  Read More
Pyridazine derivatives act as phosphodiesterase-III, IV, and V Inhibitors
7. Pyridazine derivatives act as phosphodiesterase-III, IV, and V Inhibitors

Saad Alghamdi; Mohammad Asif

Volume 1, Issue 3 , July 2021, , Pages 116-124

http://dx.doi.org/10.22034/jaoc.2021.289851.1024

Abstract
  Pyridazine derivatives are significant bioactive molecules having wide range of biological activities. Phosphodiesterase (PDE) enzymes, particularly PDE-III, PDE-IV, and PDE-V are inhibited ...  Read More
Green synthesis, characterization and biological activity of aryl Azo Schiff bases
8. Green synthesis, characterization and biological activity of aryl Azo Schiff bases

Ravindra S shinde; Nanda S. Korde; Rahul A More

Volume 1, Issue 4 , October 2021, , Pages 165-173

http://dx.doi.org/10.22034/jaoc.2021.292290.1026

Abstract
  We report a novel and eco-friendly methods approving the green synthesis of various Schiff’s bases by sonication, microwave irradiation, stirring and grinding methods using DHE ...  Read More
Meglumine Catalysed Green Synthesis of Ethyl-6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylate Derivatives
9. Meglumine Catalysed Green Synthesis of Ethyl-6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylate Derivatives

Ganesh Baburao Pund; Sambhaji Tukaram Dhumal; Madhav Janardan Hebade; Mazahar Farooqui; Bhagwansing Shivsing Dobhal

Volume 2, Issue 1 , January 2022, , Pages 15-23

http://dx.doi.org/10.22034/jaoc.2022.324493.1046

Abstract
  An efficient and simple one-pot synthetic protocol has been developed for the first time to synthesize the series of Ethyl-6-amino-5-cyano-2-methyl-4-phenyl-4H-pyran-3-carboxylates. ...  Read More
Ninhydrin as a novel and efficient catalyst for the synthesis of 2-amino-4H-Pyran derivatives in aqueous media using
10. Ninhydrin as a novel and efficient catalyst for the synthesis of 2-amino-4H-Pyran derivatives in aqueous media using

Bita Baghernejad; Mahsa Fiuzat

Volume 1, Issue 1 , February 2021, , Pages 17-21

http://dx.doi.org/10.22034/jaoc.2021.277050.1007

Abstract
  < p>Benzopyranes and their derivatives are of interest due to their wide range of biological and medicinal properties. In this study, 2-amino-4H-pyran derivatives were obtained ...  Read More
A comparison between density functional theory calculations and the additive schemes of polarizabilities of the Li-F-decorated BN cages
11. A comparison between density functional theory calculations and the additive schemes of polarizabilities of the Li-F-decorated BN cages

Maryam Anafcheh

Volume 1, Issue 3 , July 2021, , Pages 125-133

http://dx.doi.org/10.22034/jaoc.2021.292384.1027

Abstract
  We have applied density functional theory calculations to study the polarizabilities of the LiF decorated B12N12 cages (B12N12LinFn derivatives, n=1-12). The mean polarizability of ...  Read More
The Immobilized SbFx Species on Copper or Nickel Ferrite as Magnetic Nanocatalysts for Fast and Convenient Reduction and Reductive Acetylation of Nitroarenes as well Acetylation f Arylamines
12. The Immobilized SbFx Species on Copper or Nickel Ferrite as Magnetic Nanocatalysts for Fast and Convenient Reduction and Reductive Acetylation of Nitroarenes as well Acetylation f Arylamines

Maedeh Rabiei; behzad zeynizadeh; marzieh Khanmirzaee

Volume 1, Issue 4 , October 2021, , Pages 174-196

http://dx.doi.org/10.22034/jaoc.2021.303399.1035

Abstract
  In the study, magnetic nanoparticles (MNPs) of the immobilized SbFx species on copper or nickel ferrite as CuFe2O4@SbFx and NiFe2O4@SbFx were synthesized. Fourier-transform infrared ...  Read More
DTP/SiO2:An Efficient And Reusable Heterogeneous Catalyst For synthesis of dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives
13. DTP/SiO2:An Efficient And Reusable Heterogeneous Catalyst For synthesis of dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives

Rahul D. Kamble; Milind V. Gaikwad; Manojkumar R. Tapare; Shrikant V Hese; Shuddhodan N Kadam; Ajay N Ambhore; Bhaskar S. Dawane

Volume 1, Issue 1 , February 2021, , Pages 22-28

http://dx.doi.org/10.22034/jaoc.2021.276239.1004

Abstract
  An efficient and convenient method has been developed for the synthesis of 2-amino-5-oxo-4-phenyl-4, 5-dihydropyrano[3,2-c]chromene-3-carbonitrile derivatives from one-pot multicomponent ...  Read More
Simple, Highly efficient synthesis of 2-amino-4-phenyl-4,5,6,7-tetrahydropyrano[3,2-c]carbazole-3-carbonitrile derivatives using silica supported dodeca-tungstophosphoric acid DTP/SiO2
14. Simple, Highly efficient synthesis of 2-amino-4-phenyl-4,5,6,7-tetrahydropyrano[3,2-c]carbazole-3-carbonitrile derivatives using silica supported dodeca-tungstophosphoric acid DTP/SiO2

Sunil Gaikwad; Murali Venkata Basavanag Unnamatla

Volume 2, Issue 1 , January 2022, , Pages 24-30

http://dx.doi.org/10.22034/jaoc.2022.332760.1049

Abstract
  The one-pot multicomponent efficient and easily operational protocol has been developed for the synthesis of tetrahydropyrano[2,3-c]pyrazole-5-carbonitrile derivatives. The methods ...  Read More
Glycine: An Efficient Catalyst for the Synthesis of Tetra-Substituted Imidazole Derivatives in Aqueous Medium
15. Glycine: An Efficient Catalyst for the Synthesis of Tetra-Substituted Imidazole Derivatives in Aqueous Medium

Jitendra Bhausaheb Gujar; Balaji Shahaji Londhe; Raghunath Narayan Zambare; Rajesh Janardan Kavade; Murlidhar Shridhar Shingare

Volume 1, Issue 3 , July 2021, , Pages 134-142

http://dx.doi.org/10.22034/jaoc.2021.294427.1030

Abstract
  A single-pot, tandem reaction in which cyclization through condensation of 1, 2-diphenylethane-1, 2-dione, benzaldehyde, aniline, and ammonium acetate has been accomplished by orthodox ...  Read More
The Use of Silica@Zn+2 as an efficient catalyst in Diels–Alder reactions
16. The Use of Silica@Zn+2 as an efficient catalyst in Diels–Alder reactions

G. Mohammadi Ziarani; Soheila Afsharnia; alireza badiei; Negar Lashgari

Volume 1, Issue 4 , October 2021, , Pages 197-201

http://dx.doi.org/10.22034/jaoc.2021.314165.1039

Abstract
  In this study, the application of the Diels-Alder cycloaddition reactions between methyl acrylate and cyclopentadiene has been studied using a silica-supported catalyst with various ...  Read More
Computational Chemistry Approach for the Investigation of Structural, Electronic, Chemical and Quantum Chemical Facets of Twelve Biginelli Adducts
17. Computational Chemistry Approach for the Investigation of Structural, Electronic, Chemical and Quantum Chemical Facets of Twelve Biginelli Adducts

Vishnu A Adole

Volume 1, Issue 1 , February 2021, , Pages 29-40

http://dx.doi.org/10.22034/jaoc.2021.278598.1009

Abstract
  The rising concerns about the Biginelli reaction are mainly attributable to the therapeutic and pharmacological features of Biginelli adducts, especially dihydropyrimidinones (DHPMs). ...  Read More
Bi(OTf)3 as a Highly Potent Catalyst for the Synthesis of Mannich Bases under milder Conditions
18. Bi(OTf)3 as a Highly Potent Catalyst for the Synthesis of Mannich Bases under milder Conditions

Somnath Udgire; Milind Gaikwad; Prakash Patil

Volume 2, Issue 1 , January 2022, , Pages 31-38

http://dx.doi.org/10.22034/jaoc.2022.336265.1052

Abstract
  Abstract : A simple, eco-friendly friendly, and efficient procedure for the synthesis of Mannich Bases have been developed via multi-component and one-pot reactions of various aldehydes ...  Read More
New advances on Modulating nanomagnetic cores as the MRI-monitored drug release in cancer
19. New advances on Modulating nanomagnetic cores as the MRI-monitored drug release in cancer

Fatemeh Mohajer; Ghodsi Mohammadi Ziarani; Alireza Badiei

Volume 1, Issue 3 , July 2021, , Pages 143-147

http://dx.doi.org/10.22034/jaoc.2021.301405.1032

Abstract
  Multifunctional magnetic nanostructures were considered by different functional organic groups to use as a drug delivery arrangement in cancer therapy. The modulating nonmagnetic core-shell, ...  Read More
Isolation and characterization of bis(2-ethylheptyl) phthalate from Cynodon dactylon (L.) and studies on catalytic activity of its Cu(II) complex in the green preparation of 1,8-dioxo-octahydroxanthenes
20. Isolation and characterization of bis(2-ethylheptyl) phthalate from Cynodon dactylon (L.) and studies on catalytic activity of its Cu(II) complex in the green preparation of 1,8-dioxo-octahydroxanthenes

Ali Allahresani; Fatemeh Ghorbanian; Mohammad Ali Nasseri; Milad Kazemnejadi

Volume 2, Issue 1 , January 2022, , Pages 39-53

http://dx.doi.org/10.22034/jaoc.2022.149417

Abstract
  Bis(2-ethylheptyl) phthalate is an anti-oxidant and anticancer compound that was extracted from the Cynodon dactylon plant stem extract and fully identified and characterized by FTIR, ...  Read More
Quantum chemical and molecular docking studies of some phenothiazine derivatives
21. Quantum chemical and molecular docking studies of some phenothiazine derivatives

Ganesan Venkatesh; Yohannan Sheena mary; Y. Shymamary; Vennila Palanisamy; M. Govindaraju

Volume 1, Issue 3 , July 2021, , Pages 148-158

http://dx.doi.org/10.22034/jaoc.2021.303059.1033

Abstract
  Phenothiazines are synthetic antipsychotics with a wide range of biological effects. Their properties are determined by the structure and variety of substituents in the heterocyclic ...  Read More
Synthesis, Spectral and Biological Studies of DHA Schiff Bases
22. Synthesis, Spectral and Biological Studies of DHA Schiff Bases

Shubham Bhagwatrao Biradar; Dnyaneshwar Vithal Narte; Rushikesh Pradip Kale; Kalimoddin Inayatsab Momin; Maroti Sayabu Sudewad; Kundan Chandramani Tayade; Dhananjay Gangadhar Palke

Volume 1, Issue 1 , February 2021, , Pages 41-47

http://dx.doi.org/10.22034/jaoc.2021.275758.1003

Abstract
  ABSTRACTA new series of Schiff bases derived from DHA (Dehydroacetic acid) and aromatic primary amines were synthesized and characterized by elemental and spectral (Electronic, IR and ...  Read More
Anti-microbial evaluation, Experimental and Theoretical Insights into Molecular Structure, Electronic Properties, and Chemical Reactivity of (E)-2-((1H-indol-3-yl)methylene)-2,3-dihydro-1H-inden-1-one
23. Anti-microbial evaluation, Experimental and Theoretical Insights into Molecular Structure, Electronic Properties, and Chemical Reactivity of (E)-2-((1H-indol-3-yl)methylene)-2,3-dihydro-1H-inden-1-one

Rahul Shinde; Vishnu A Adole

Volume 1, Issue 2 , April 2021, , Pages 48-58

http://dx.doi.org/10.22034/jaoc.2021.278742.1011

Abstract
  The present investigation describes antimicrobial, computational, study of (E)-2-((1H-indol-3-yl)methylene)-2,3-dihydro-1H-inden-1-one (IMDHI) molecule. The spectroscopic characterization ...  Read More
Computational Investigation of Infrared Vibrational Frequency Shift Modes in Schiff Base-Transition Metal Complexes
24. Computational Investigation of Infrared Vibrational Frequency Shift Modes in Schiff Base-Transition Metal Complexes

Chidi E Duru; Ijeoma Duru

Volume 2, Issue 2 , May 2022, , Pages 54-65

http://dx.doi.org/10.22034/jaoc.2022.319433.1041

Abstract
  The computational investigation of change in the infrared vibrational frequency of some Schiff base-transition metal complexes relative to that observed in the Schiff base ligand was ...  Read More
Regioselective One-pot transformation of 2’-hydroxy chalcones to 3,5-diphenylisoxazole via dehydrogenation of dihydroisoxazolines using Copper salt in DMF
25. Regioselective One-pot transformation of 2’-hydroxy chalcones to 3,5-diphenylisoxazole via dehydrogenation of dihydroisoxazolines using Copper salt in DMF

Milind V Gaikwad

Volume 1, Issue 2 , April 2021, , Pages 59-65

http://dx.doi.org/10.22034/jaoc.2021.278705.1010

Abstract
  A synthesis of series of 3, 5-diaryl isoxazoles has been described. The Cu salt in DMF with EDU base induces oxidative dehydrogenation of 2-(5-phenyl-4,5-dihydroisoxazol-3-yl) phenol ...  Read More